Wound Healing Effects of Aqueous Leave Extracts of Azadirachta Indica: the Wound Healing Effects of Aqueous Leave Extracts of Azadirachta Indica on Wistar Rats

The mechanism of tissue healing is a complex biological process that involves a perfect and coordinated cascade of cellular and molecular events promoting tissue reconstitution. This process arises as a response of the tissue to injuries induced by trauma or by surgical procedures. The process of wound healing is characterized by four phases that overlap and present a characteristic profile: Hemostasis, inflammatory phase, proliferative phase and remodeling phase. Despite some recent advances in the understanding of these basic processes, wound healing disorders continue to cause diseases and even death. The application of phyto-therapeutic agents has also shown to be highly effective in the healing of wounds and burns.